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Resequencing the Vrs1 gene in Spanish barley landraces revealed reversion of six-rowed to two-rowed spike

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dc.creator Casas Cendoya, Ana Maria
dc.creator Contreras‐Moreira, Bruno
dc.creator Cantalapiedra, Carlos P.
dc.creator Sakuma, Shun
dc.creator Gracia Gimeno, Ma. Pilar
dc.creator Moralejo Vidal, Mª Angeles
dc.creator Molina Cano, José Luis
dc.creator Komatsuda, Takao
dc.creator Igartua Arregui, Ernesto
dc.date 2018-04-12
dc.date.accessioned 2025-11-03T12:17:38Z
dc.date.available 2025-11-03T12:17:38Z
dc.identifier https://doi.org/10.1007/s11032-018-0816-z
dc.identifier 1380-3743
dc.identifier http://hdl.handle.net/10459.1/69847
dc.identifier.uri http://fima-docencia.ub.edu:8080/xmlui/handle/123456789/24554
dc.description Six-rowed spike 1 (Vrs1) is a gene of major importance for barley breeding and germplasm management as it is the main gene determining spike row-type (2-rowed vs. 6-rowed). This is a widely used DUS trait, and has been often associated to phenotypic traits beyond spike type. Comprehensive re-sequencing Vrs1 revealed three two-rowed alleles (Vrs1.b2; Vrs1.b3; Vrs1.t1) and four six-rowed (vrs1.a1; vrs1.a2; vrs1.a3; vrs1.a4) in the natural population. However, the current knowledge about Vrs1 alleles and its distribution among Spanish barley subpopulations is still underexploited. We analyzed the gene in a panel of 215 genotypes, made of Spanish landraces and European cultivars. Among 143 six-rowed accessions, 57 had the vrs1.a1 allele, 83 were vrs1.a2, and three showed the vrs1.a3 allele. Vrs1.b3 was found in most two-rowed accessions, and a new allele was observed in 7 out of 50 two-rowed Spanish landraces. This allele, named Vrs1.b5, contains a ‘T’ insertion in exon 2, originally proposed as the causal mutation giving rise to the six-row vrs1.a2 allele, but has an additional upstream deletion that results in the change of 15 amino acids and a potentially functional protein. We conclude that eight Vrs1 alleles (Vrs1.b2, Vrs1.b3, Vrs1.b5, Vrs1.t1, vrs1.a1, vrs1.a2, vrs1.a3, vrs1.a4) discriminate two and six-rowed barleys. The markers described will be useful for DUS identification, plant breeders, and other crop scientists.
dc.description This work was supported by the Spanish Ministry of Economy, Industry and Competitiveness grants AGL2010-21929, AGL2013-48756-R, RFP2012-00015-00-00, RTA2012-00033-C03-02, and EUI2009-04075 (national code for Plant-KBBE project ExpResBar). CPC was funded by the Spanish Ministry of Economy, Industry and Competitiveness grant no. BES-2011-045905 (linked to project AGL2010-21929). TK and SS were supported by a research fund by the Ministry of Agriculture, Forestry, and Fisheries of Japan (Genomics for Agricultural Innovation grants no. TRS1002). SS was supported by a Grant-in-Aid from the Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellow for Research Abroad and a Grant-in-Aid for Young Scientists (B) (no. 16 K18635).
dc.language eng
dc.publisher Springer Science+Business Media B.V., part of Springer Nature
dc.relation info:eu-repo/grantAgreement/MICINN//AGL2010-21929/ES/DESCUBRIMIENTO DE NUEVA VARIABILIDAD PARA LA MEJORA DE LA CEBADA EN ESPAÑA/
dc.relation info:eu-repo/grantAgreement/MINECO//AGL2013-48756-R/ES/DESCUBRIMIENTO Y UTILIZACION DE LA VARIABILIDAD GENETICA QUE DETERMINA LA ADAPTACION DE LA CEBADA MEDIANTE HERRAMIENTAS GENETICAS, GENOMICAS/
dc.relation info:eu-repo/grantAgreement/MINECO//RFP2012-00015-00-00/ES/
dc.relation info:eu-repo/grantAgreement/MINECO//RTA2012-00033-C03-02/ES/Obtención de variedades de cebada de calidad con amplia adaptación en España/
dc.relation info:eu-repo/grantAgreement/MICINN//EUI2009-04075/ES/EXPLOITING GENETIC VARIATION FOR RESISTANCE TO IMPORTANT PATHOGENS IN BARLEY/
dc.relation info:eu-repo/grantAgreement/MICINN//BES-2011-045905/ES/BES-2011-045905/
dc.relation Versió postprint del document publicat a: https://doi.org/10.1007/s11032-018-0816-z
dc.relation Molecular Breeding, 2018, vol. 38, p. 51
dc.rights (c) Springer Science+Business Media B.V., part of Springer Nature, 2018
dc.rights info:eu-repo/semantics/openAccess
dc.subject Barley
dc.subject Landraces
dc.subject Vrs1
dc.subject SNP
dc.title Resequencing the Vrs1 gene in Spanish barley landraces revealed reversion of six-rowed to two-rowed spike
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/acceptedVersion


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