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Lymphocyte populations in liver biopsy specimens from patients with chronic liver disease

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dc.creator Sánchez Tapias, José M. (José María)
dc.creator Thomas, H. C.
dc.creator Sherlock, Sheila, Dame
dc.date 2011-07-07T12:31:03Z
dc.date 2011-07-07T12:31:03Z
dc.date 1977
dc.date.accessioned 2024-12-16T10:27:16Z
dc.date.available 2024-12-16T10:27:16Z
dc.identifier 0017-5749
dc.identifier http://hdl.handle.net/2445/18679
dc.identifier 11139
dc.identifier 326639
dc.identifier.uri http://fima-docencia.ub.edu:8080/xmlui/handle/123456789/22181
dc.description The characterisation of lymphocytes from liver biopsies indicates that 'activated' T lymphocytes are present in the liver in alcohol induced hepatitis, chronic active hepatitis (HBS+ve and -ve), and in primary biliary cirrhosis but not in inactive cirrhosis, chronic persistent hepatitis, extrahepatic and drug induced cholestasis. A greater percentage of lymphocytes bear Fc-receptors in chronic active hepatitis than in alcohol induced hepatitis or cholestatic liver disease. The concentration of 'activated' T cells in the peripheral blood in all groups studied was within the normal range, suggesting that the 'activated' T cells found in the liver were reacting to either native or foreign antigens within the liver. The data on Fc-receptor bearing cells are consistent with the involvement of antibody assisted K cell mediated cytotoxicity in chronic active hepatitis.
dc.format 4 p.
dc.format application/pdf
dc.language eng
dc.publisher BMJ Group
dc.relation Reproducció digital del document publicat a: http://dx.doi.org/doi:10.1136/gut.18.6.472
dc.relation Gut, 1977, vol. 18, núm. 6, p. 472-475
dc.rights (c) BMJ Publishing Group Ltd and British Society of Gastroenterology, 1977
dc.rights info:eu-repo/semantics/openAccess
dc.source Articles publicats en revistes (Medicina)
dc.subject Malalties del fetge
dc.subject Limfòcits
dc.subject Biòpsia
dc.subject Liver diseases
dc.subject Lymphocytes
dc.subject Byopsy
dc.title Lymphocyte populations in liver biopsy specimens from patients with chronic liver disease
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion


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