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The role of cellular contractility in topography sensing on soft nanoporous polyacrylamide hydrogels

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dc.contributor Comelles Pujadas, Jordi
dc.creator Rebollo Calderón, Beatriz
dc.date 2018-11-19T10:33:01Z
dc.date 2018-11-19T10:33:01Z
dc.date 2018-11
dc.date.accessioned 2024-12-16T10:27:04Z
dc.date.available 2024-12-16T10:27:04Z
dc.identifier http://hdl.handle.net/2445/126206
dc.identifier.uri http://fima-docencia.ub.edu:8080/xmlui/handle/123456789/21834
dc.description Màster en Nanociència i Nanotecnologia, Facultat de Física, Universitat de Barcelona, Curs: 2017-2018. Tutor: Jordi Comelles
dc.description Extracellular matrix physical characteristics have been shown to play an important role in cellular processes such as adhesion, migration, proliferation and differentiation. Of high importance are the stiffness and the topography of the extracellular matrix, which are believed to activate shared signalling pathways to cause a cellular response. In this work, we use polyacrylamide nanoporous hydrogels of different stiffness, both with and without microtopographical structures to see if these physical cues are truly sensed by the same mechanism, and an inhibitor of ROCK I to determine the role of cell contractility in the sensing of topography and stiffness
dc.format 10 p.
dc.format application/pdf
dc.language eng
dc.rights cc-by-nc-nd (c) Rebollo, 2018
dc.rights http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights info:eu-repo/semantics/openAccess
dc.source Màster Oficial - Nanociència i Nanotecnologia
dc.subject Ultraestructura (Biologia)
dc.subject Matriu extracel·lular
dc.subject Treballs de fi de màster
dc.subject Ultrastructure (Biology)
dc.subject Extracellular matrix
dc.subject Master's theses
dc.title The role of cellular contractility in topography sensing on soft nanoporous polyacrylamide hydrogels
dc.type info:eu-repo/semantics/masterThesis


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