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Spontaneous activity in neuronal networks with dictated connectivity

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dc.contributor Soriano i Fradera, Jordi
dc.creator Ortiz Miquel, Olga
dc.date 2018-10-08T16:59:15Z
dc.date 2018-10-08T16:59:15Z
dc.date 2018-06
dc.date.accessioned 2024-12-16T10:26:49Z
dc.date.available 2024-12-16T10:26:49Z
dc.identifier http://hdl.handle.net/2445/125149
dc.identifier.uri http://fima-docencia.ub.edu:8080/xmlui/handle/123456789/21551
dc.description Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2018, Tutor: Jordi Soriano Fradera
dc.description We studied spontaneous activity in rat neuronal cultures and compared two configurations, namely homogeneous and patterned. In the former, neurons grew over a plain glass substrate and therefore could develop isotropically. In the latter, neurons grew on a substrate shaped with topographical obstacles, which dictated the connectivity of the neurons and broke the isotropy of the system. Activity in all networks was recorded using fluorescence calcium imaging. By analyzing and comparing their activity patterns, we have found that activity in patterned cultures is markedly different, with richer spatiotemporal activity fronts and slower propagation speeds.
dc.format 5 p.
dc.format application/pdf
dc.language eng
dc.rights cc-by-nc-nd (c) Ortiz, 2018
dc.rights http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights info:eu-repo/semantics/openAccess
dc.source Treballs Finals de Grau (TFG) - Física
dc.subject Xarxes neuronals (Neurobiologia)
dc.subject Cultiu cel·lular
dc.subject Treballs de fi de grau
dc.subject Neural networks (Neurobiology)
dc.subject Cell culture
dc.subject Bachelor's theses
dc.title Spontaneous activity in neuronal networks with dictated connectivity
dc.type info:eu-repo/semantics/bachelorThesis


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