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Initiation and propagation of activity in neuronal cultures under connectivity alterations

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dc.contributor Soriano i Fradera, Jordi
dc.creator Herrera Carrillo, Jose Arnau
dc.date 2018-10-04T15:40:59Z
dc.date 2018-10-04T15:40:59Z
dc.date 2018-06
dc.date.accessioned 2024-12-16T10:26:47Z
dc.date.available 2024-12-16T10:26:47Z
dc.identifier http://hdl.handle.net/2445/125071
dc.identifier.uri http://fima-docencia.ub.edu:8080/xmlui/handle/123456789/21522
dc.description Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2018, Tutor: Jordi Soriano Fradera
dc.description Activity in living neuronal networks is governed by complex laws that are still poorly understood. To advance in this quest, we study the initiation and propagation of activity fronts in in vitro neuronal networks. We consider two major experiments in which we modify the connectivity of the network. In a first one, we physically cut a region of the culture. I a second one we apply a drug that changes the connectivity of the network. In both experiments, we determine the velocity of the activity fronts, their timing and the point of origin. We frame our results in the context of the noise focusing phenomena, a mechanism that explains the initiation of activity in terms of network connectivity, neuronal dynamics, and amplification of noise
dc.format 5 p.
dc.format application/pdf
dc.language eng
dc.rights cc-by-nc-nd (c) Herrera, 2018
dc.rights http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights info:eu-repo/semantics/openAccess
dc.source Treballs Finals de Grau (TFG) - Física
dc.subject Xarxes neuronals (Neurobiologia)
dc.subject Soroll
dc.subject Treballs de fi de grau
dc.subject Neural networks (Neurobiology)
dc.subject Noise
dc.subject Bachelor's theses
dc.title Initiation and propagation of activity in neuronal cultures under connectivity alterations
dc.type info:eu-repo/semantics/bachelorThesis


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