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Genome sequence of the pea aphid Acyrthosiphon pisum

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dc.creator Rozas Liras, Julio A.
dc.creator Vieira, Filipe G.
dc.creator International Aphid Genomics Consortium
dc.date 2010-06-14T09:28:35Z
dc.date 2010-06-14T09:28:35Z
dc.date 2010
dc.date.accessioned 2024-12-16T10:24:28Z
dc.date.available 2024-12-16T10:24:28Z
dc.identifier 1544-9173
dc.identifier http://hdl.handle.net/2445/12883
dc.identifier 573971
dc.identifier 20186266
dc.identifier.uri http://fima-docencia.ub.edu:8080/xmlui/handle/123456789/17736
dc.description Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.
dc.format 24 p.
dc.format application/pdf
dc.language eng
dc.publisher PLoS
dc.relation Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pbio.1000313
dc.relation PLoS Biol, 2010, vol. 8, núm. 2, e1000313
dc.relation http://dx.doi.org/10.1371/journal.pbio.1000313
dc.rights cc-by,(c) The International Aphid Genomics Consortium, 2010
dc.rights http://creativecommons.org/licenses/by/3.0/es/
dc.rights info:eu-repo/semantics/openAccess
dc.source Articles publicats en revistes (Genètica, Microbiologia i Estadística)
dc.subject Sequència genòmica
dc.subject Afídids
dc.subject Genome Sequence
dc.subject Aphids
dc.title Genome sequence of the pea aphid Acyrthosiphon pisum
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion


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